2026
101. Ullah, M.; Shahriar, K.; Mustafa, M.B.; Best, M.D. Cysteine-responsive lipid switch development for liposome triggered cargo release. In Press. DOI: 10.1021/acs.bioconjchem.6c00392.
100. Ullah, M.; Cannon, J.A.; Reynolds, T.B.; Best, M.D. A FRET-based fluorometric assay for tracking the enzymatic degradation of poly-L-lactic acid. Biomacromolecules In Press. DOI: 10.1021/acs.biomac.6c01709.
99. Smith, B.E.; Lou, J.; Phillips, M.A.; Sagar, R.; Qualls, M.; McBee, D.P.; Turner, R.F.; Ullah, M.; Baccile, J.A.; Best, M.D.* A synergistic approach using a ROS-responsive lipid-based prodrug for liposomal delivery of doxorubicin. Bioconjugate Chem. In Press. DOI: 10.1021/acs.bioconjchem.6c00165.
98. Maraski, R.J.; Best, M.D. Recent advancements in phospholipid metabolic labeling using clickable probes. Biochemistry DOI 10.1021/acs.biochem.6c00535.
97. Maraski, R.J.; Lou, J.; Reynolds, T.B.; Best, M.D.* Metabolic labeling of phosphatidylethanolamine lipids in cells using clickable ethanolamine analogs. ChemBioChem 2026, 27, e70501. DOI: 10.1002/cbic.70501
96. Shahriar, K.R.; Mustafa, M.B.; Kaufman, N.R.; Best, M.D.* De novo lipid switch design for reactive oxygen species-triggered liposomal release. Bioconjugate Chem. 2026, 37(7), 1475-1482.
95. Hansen, A.; Mustafa, M.B.; Lou, J.; Best, M.D.* Enhancing triggered release of polar cargo from ROS-responsive liposomes. Bioconjugate Chem. 2026, 37(6), 1249-1256.
94. Smith, B.E.; Russell, C.G.; Mustafa, M.B.; Best, M.D.* Engineering tunable GTP/TPi-responsive liposomes through membrane modulation using a bis-triphenylphosphonium lipid switch. RSC Pharmaceutics. 2026, 3, 256-264.
93. Moore, W.M.; Brea, R.J.; Knittel, C.; Wrightsman, E.; Hui, B.; Lou, J.; Ancajas, C.F.; Best, M.D.; Devaraj, N.K.; Budin, I.* Leaflet-specific phospholipid imaging using genetically encoded proximity sensors. Nat. Chem. Biol. 2026, 22(1), 128-139.
92. Maraski, R.J.; Ancajas, C.F.; Lou, J.; Best, M.D.* Metabolic labeling of glycerophospholipids. Meth. Enzymol. 2026. DOI 10.1016/bs.mie.2025.11.010.
2025
91. Mustafa, M.B.; Lou, J.; Best, M.D.* Development of ROS-responsive liposomes toward targeted drug delivery. Exp. Opin. Drug Deliv. 2025, 22(11), 1709-1725. DOI 10.1080/17425247.2025.2556013.
90. Limbach, M.N.; Lindberg, E.T.; Shrestha, C.; Lou, J.; Steren, C.A.; Best, M.D.; Do, T.D.* Biased equilibrium drives cyclosporine membrane permeability: The Goldilocks of energy barriers. J. Med. Chem. 2025, 68(6), 6588-6600.
89. Mustafa, M.B., Lou, J., Phillips, M.A., Turner, R., Baccile, J.A., Best, M.D.* Development of ROS-triggered masked liposomes for activated cellular delivery using a charge balance strategy. Chem. Commun. 2025, 61. 3131-3134.
88. Mehta, D.; Crumley. E.; Lou, J.; Best, M.D.; Waxham, N.; Heberle, F.A.* Halogenated cholesterol alters the phase behavior of ternary lipid membranes. J. Phys Chem B. 2025, 129 (2), 671–683.
2024
87. Lou, J.; Ancajas, C.F.; Zhou, Y.; Lane, N.; Reynolds, T.B.; Best, M.D.* Probing glycerolipid metabolism using a caged clickable glycerol-3-phosphate probe. ChemBioChem. 2024, 25 (18), e202300853.
86. Zhou, Y.; Phelps, G.A.; Mangrum, M.; McLeish, J.; Phillips, E.K.; Lou, J.; Ancajas, C.F.; Rybak, J.M.; Oelkers, P.; Lee, R.E.; Best, M.D.; Reynolds, T.B.* The small molecule CBR-5884 inhibits the Candida albicans phosphatidylserine synthase. mBio. 2024, e00633-24.
85. Jung, O.; Baek, M.-J.; Wooldrik, C.; Johnson, K.R.; Fisher, K.W.; Lou, J.; Ricks, T.J.; Best, M.D.; Cryns, V.L.; Anderson, R.A.; Choi, S.* Nuclear phosphoinositide signaling controls the YAP/TAZ-TEAD pathway in breast cancer. EMBO J. 2024, 43, 1740-1769.
2023
84. Sagar, R.; Lou, J.; Best, M.D.*Development of a bis-pyrene phospholipid probe for fluorometric detection of phospholipase A2 inhibition. Bioorg. Med. Chem. 2023, 117310.
83. Ancajas, C.F.; Carr, A.J.; Lou, J.; Sagar, R.; Zhou, Y.; Reynolds, T.B.; Best, M.D.* Harnessing clickable acylated glycerol probes as chemical tools for tracking lipid metabolism. Chem. Eur. J. 2023, e202300417.
82. Lou, J.; Hudson, M.; Ancajas, C.F.; Best, M.D.* Development of GTP-responsive liposomes by exchanging the metal-DPA binding site in a synthetic lipid switch. Chem. Commun. 2023, 59, 3285-3288.
81. Ancajas, C.F.; Alam, S.; Alves, D.A.; Zhou, Y.; Wadsworth, N.M.; Cassilly, C.D.; Ricks, T.J.; Carr, A.J.; Reynolds, T.B.; Barrera, F.N.; Best, M.D.* Cellular labeling of phosphatidylserine using clickable serine probes. ACS Chem. Biol. 2023, 18(2), 377-384.
80. Sagar, R.; Jaremba, E.A.; Lou, J.; Best, M.D.* Copper-responsive liposomes for triggered Cargo release employing a picolinamide-lipid conjugate. Org. Biomol. Chem. 2023, 21, 955-959. DOI: 10.1039/D2OB01977A.
79. Lou, J.; Qualls, M.; Best, M.D.* Sticking the landing: Enhancing liposomal cell delivery using reversible covalent chemistry and caged targeting groups. ChemBioChem, 2023, 24(2), e202200436. DOI: 10.1002/cbic.202200436.
2022
78. Lou, J.; Sagar, R.; Best, M.D.* Metabolite-responsive liposomes employing synthetic lipid switches driven by molecular recognition principles. Acc. Chem. Res. 2022. DOI: 10.1021/acs.accounts.2c00446.
77. Qualls, M.; Hagewood, H.; Lou, J.; Mattern-Schain, S.I.; Zhang. X.; Mountain, D.J.; Best, M.D.* Bis-boronic acid liposomes for carbohydrate recognition and cellular delivery. ChemBioChem. 2022, e202200402. DOI: 10.1002/cbic.202200402.
76. Qualls, M.L.; Lou, J.; McBee, D.P.; Baccile, J.A.; Best, M.D.* Cyclic disulfide lipids for membrane functionalization and cellular delivery. Chem. Eur. J. 2022 28(45), e2022011. DOI: 10.1002/chem.202201164.
75. Lou, J.; Qualls, M.L.; Hudson, M.M.; McBee, D.P.; Baccile, J.A.; Best, M.D.* Reactive oxygen species (ROS) activated liposomal cell delivery using a boronate-caged guanidine lipid. Chem. Eur. J. 2022, 28(46), e202201057. DOI: 10.1002/chem.202201057.
74. Bottcher, S.; Lou, J.; Best, M.D.* Liposome triggered content release through molecular recognition of inositol trisphosphate. Chem. Commun. 2022, 58, 4520-4523, DOI: 10.1039/d2cc00951j.
73. Lou, J.; Schuster, J.; Barrera, F.N.; Best, M.D.* ATP-Responsive liposomes developed by screening lipid switches designed to undergo conformational changes upon binding phosphorylated metabolites. J. Am. Chem. Soc. 2022, 144, 3746-3756. DOI 10.1021/jacs.2c00191.
72. Gray, A.L.; Sawaya, M.R.; Acharyya, D.; Lou, J.; Edington, E.; Best, M.D.; Prosser, R.A.; Eisenberg, D.S.; Do, T.D.* Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices. Protein Sci. 2022, 31(3), 716-727. DOI 10.1002/pro.4268
2021
71. Sagar, R.; Lou, J.; Watson, A.; Best, M.D.* Zinc Triggered Release of Encapsulated Cargo from Liposomes via a Synthetic Lipid Switch. Bioconjugate Chem. 2021, 32(12), 2485-2496. DOI: 10.1021/acs.bioconjchem.1c00425.
70. Qualls, M.; Sagar, R.; Lou, J.; Best, M.D. Demolish and rebuild: Controlling membrane self-assembly using toward triggered release and artificial cells. J. Phys. Chem. B. 2021, 125, 12918-12933. DOI: 10.1021/acs.jpcb.1c07406.
69. Fisher, R.K.; West, P.C.; Mattern-Schain, S.I.; Best, M.D.; Kirkpatrick, S.S.; Dieter, R.A.; Arnold, J.D.; Buckely, M.R.; McNally, M.M.; Freeman, M.B.; Grandas, O.H.; Mountain D.J.H. Advances in the formulation and assembly of non-cationic lipid nanoparticles for the medical application of gene therapeutics. Nanomaterials 2021, 11(3), 825. DOI: 10.3390/nano11030825
68. Olson, J.; Hu, Z.; Best, M.D.; Jensen, L.; Camden, J.P. Surface-enhanced hyper-Raman scattering of rhodamine 6G isotopologues: Assignment of low vibrational frequencies. J. Chem. Phys. 2021, 154, 034703. DOI: 10.1063/5.0031679
2020
67. Ancajas, C.F.; Ricks, T.J.; Best, M.D.* Metabolic labeling of glycerophospholipids via clickable analogs derivatized at the lipid headgroup. Chem. Phys. Lipids 2020, 232, 104971. DOI 10.1016/j.chemphyslip.2020.104971.
66. Lou, J.; Best, M.D.* Strategies for altering lipid self-assembly to trigger liposome cargo release. Chem. Phys. Lipids 2020, 232, 104966. DOI 10.1016/j.chemphyslip.2020.104966.
65. Lou, J. Best, M.D.* Reactive oxygen species-responsive liposomes via boronate-caged phosphatidylethanolamine. Bioconjugate Chem. 2020, 31, 2220-2230. DOI 10.1021/acs.bioconjchem.0c00397.
64. Lou, J.; Best, M.D. Calcium-responsive liposomes: Toward ion-mediated targeted drug delivery. Meth. Enzymol. 2020, 640, 105-129. DOI 10.1016/bs.mie.2020.04.005.
63. Lou, J.; Best, M.D. A general approach to enzyme-responsive liposomes. Chem. Eur. J. 2020, 26, 8597 –8607. DOI 10.1002/chem.202000529.
2019
62. Mattern-Schain, S.I.; Fisher, R.K.; West, P.C.; Kirkpatrick, S.S.; Best, M.D.;* Mountain, D.J.H.* Cell mimetic liposomal nanocarriers for tailored delivery of vascular therapeutics. Chem. Phys. Lipids. 2019, 218, 149-157.
61. Lou, J.; Zhang, X.; Best, M.D. Lipid switches: Stimuli-responsive liposomes via conformational isomerism driven by molecular recognition. Chem. Eur. J. 2019, 25, 20-25.
60. Ricks, T.J.; Cassilly, C.D.; Carr, A.J.; Alam, S.; Tscherch, K.; Yokley, T.W.; Worman, C.E.; Alves, D.S.; Morrell-Falvey, J.L.; Barrera, F.N.; Reynolds, T.B.; Best, M.D.* Labeling of phosphatidylinositol lipid products in cells via metabolic engineering using a clickable myo-inositol probe. ChemBioChem. 2019, 20, 172-180.
2018
59. Zhang, X.; Alves, D.S.; Lou, J.; Hill, S.D.; Barrera, F.N.; Best, M.D.* Boronic acid liposomes for cellular delivery and content release driven by carbohydrate binding. Chem. Commun. 2018, 54, 6169-6172.
58. Lou, J.; Carr, A.J.; Watson, A.J.; Mattern-Schain, S.I.; Best, M.D.* Calcium-responsive liposomes via a synthetic lipid switch. Chem. Eur. J. 2018, 24, 3599-3607.
2017
57. Zhang, X.; Zhang, S.; Baek, S.J.; Best, M.D.* A boronic acid assay for the detection of mucin-1 glycoprotein from cancer cells. ChemBioChem 2017, 18, 1578-1582.
56. Whitehead, S.A.; McNitt, C.D.; Mattern-Schain, S.I.; Carr, A.J.; Alam, S.; Popik, V.V.; Best, M.D.* Artificial membrane fusion triggered by strain-promoted alkyne-azide cycloaddition. Bioconjugate Chem. 2017, 28, 923-932.
55. Alam, S.; Mattern-Schain, S.I.; Best, M.D.* Targeting and triggered release using lipid-based supramolecular assemblies as medicinal nanocarriers. In: Comprehensive Supramolecular Chemistry II, Atwood, J.L. (ed.), 2017, vol. 5, 329-364. (Book Chapter).
54. Fisher, R.K.; Mattern-Schain, S.I.; Best, M.D.; Kirkpatrick, S.S.; Freeman, M.B.; Grandas, O.H.;Mountain, D.J.H.* Improving the efficacy of liposome-mediated vascular gene therapy via lipid surface modifications. Journal of Surgical Research 2017, 219, 136-144.
2016
53. Do-Thanh, C.-L.; Vargas, J.J.; Thomas, J.W.; Armel, G.R.*; Best, M.D.* Design, synthesis and evaluation of novel auxin mimic herbicides.J. Agric. Food Chem. 2016, 64, 3533-3537.
2015
52. Alam, S.; Alves, D.S.; Whitehead, S.A.; Bayer, A.M.; McNitt, C.D.; Popik, V.V.; Barrera F.N.; Best, M.D.* A clickable and photocleavable lipid analogue for cell membrane delivery and release. Bioconjugate Chem. 2015, 26, 1021-1031.
51. Rezaee, M.; Wang, Y.; Zhang, X.; Liu, G.; Bowen, K.; Bayer, A.M.; Best, M.D.; Compton, R.N.* Negative ion properties of trans-2,2ʹ,6,6ʹ-tetrafluoroazobenzene: Experiment and theory. J. Chem. Phys. 2015, 143(11), 114303.
50. Elmore, M.*; Brosnan, J.T.; Armel, G.R.; Kopsell, D.A.; Best, M.D.; Mueller, T.C.; Sorochan, J.C. Cytochrome P450 inhibitors reduce creeping bentgrass (agrostis stolonifera) tolerance to topramezone. PLOS One 2015, DOI: 10.1371/journal.pone.0130947.
2014
49. Best, M.D.* Global approaches for the elucidation of phosphoinositide-binding proteins. Chem. Phys. Lipids 2014, 182, 19-28.
48. Bayer, A.M.; Alam, S.; Mattern-Schain, S.I.; Best, M.D.* Triggered liposomal release through a phosphatidylcholine analogue bearing a photocleavable moiety embedded within the sn-2 acyl chain. Chem. Eur. J. 2014, 20(12), 3350-3357.
47. Cutulle, M.A.*; Armel, G.R.; Brosnan, J.T.; Best, M.D. Kopsell, D.A.; Bruce, B.D.; Bostic, H.E.; Layton, D.D. Synthesis and evaluation of heterocyclic analogs of bromoxynil. J. Agric. Food Chem. 2014, 62, 329-336.
46. Crozier, K.B.*; Zhu, W.; Wang, D.; Lin, S.; Best, M.D.; Camden, J.P. Plasmonics for surface enhanced raman scattering: Nanoantennas for single molecules. J. Sel. Top. Quant. Elect. 2014, 20(3), DOI: 10.1109/JSTQE.2013.2282257.
2013
45. Best, M.D.* The development and application of clickable lipid analogs for elucidating lipid function. Click Chemistry in Glycoscience: New Developments and Strategies. Wiley and Sons, editors: Zbigniew Witczak and Roman Bielski. 2013. 79-107. (Book Chapter)
44. Wang, D.; Zhu, W.; Best, M.D.; Camden, J.P.; Crozier, K.B.* Directional Raman scattering from single molecules in the feed gaps of optical antennas. Nano Lett. 2013, 13(5), 2194-2198.
43. Liu, L.; Xie, H.; Bostic, H.E.; Jin, L.; Best, M.D.; Zhang, X.P.; Zhan, W.* Effects of oriented surface dipole on photoconversion efficiency in an alkane/lipid-hybrid-bilayer-based photovoltaic model system. ChemPhysChem, 2013, 14(12), 2777-2785.
42. Lambert, J.; Chen,J.; Buonaugurio, A.; Bowen, K.H.*; Do-Thanh, C.-L.; Wang, Y.; Best, M.D.; Compton, B.*; Sommerfeld, T. Combined photoelectron, collision-induced dissociation, and computational studies of parent and fragment anions of N-paranitrosulfophenysulfonylalanine and N-paranitrophenylalanine. J. Chem. Phys. 2013, 139, 224308.
41. Thomas, J.W.*; Armel, G.R.; Best, M.D.; Brosnan, J.T.; Klingeman, W.E.; Kopsell, D.A.; Bostic, H.E.; Vargas, J.J.; Do-Thanh, C.-L. Herbicidal activity of heterocyclic dichlobenil analogues. J. Pest. Sci. 2013, 38(4), 220-222.
40. Milojevich, C.B.; Mandrell, B.K.; Turley, H.K.; Iberi, V.; Simmons, P.D.; Best, M.D.; Camden, J.P.* Surface-enhanced hyper-Raman scattering from single molecules. J. Phys. Chem. Lett. 2013, 4, 3420-3423.
39. Wang, D.; Zhu, W.; Best, M.D.; Camden, J.P.; Crozier, K.B.* Wafer-scale metasurface for total power absorption, local field enhancement and single molecule Raman spectroscopy. Scientific Reports 2013, 3, doi:10.1038/srep02867.
2012
38. Bostic, H.E.; Smith, M.D.; Poloukhtine, A.A.; Popik, V.V.; Best, M.D.* Membrane labeling and immobilization via copper-free click chemistry. Commun. 2012, 48, 1431-1433.
37. Rowland,M.M.; Bostic, H.E.; Gong, D.; Lucas, N.; Cho, W.; Best, M.D.* Microarray analysis of Akt PH domain binding employing synthetic biotinylated analogs of all seven phosphoinositide headgroup isomers. Chem. Phys. Lipids 2012, 165, 207-215.
36. Do-Thanh, C.-L.; Khanal, N.; Lu, Z.; Cramer, S.A.; Jenkins, D.M.*; Best, M.D.* Chloride binding by a polyimidazolium macrocycle detected via fluorescence, NMR and X-ray crystallography. Tetrahedron 2012, 68, 1669-1673.
35. Mirsaleh-Kohan, M.; Iberi, V.; Simmons, P.D.; Bigelow, N.W.; Vaschillo, A.; Rowland, M.M.; Best, M.D.; Pennycook, S.J.; Masiello, D.J.*; Guiton, B.S.*; Camden, J.P.* Single-molecule surface-enhanced raman scattering: can STEM/EELS image electromagnetic hot spots? J. Phys. Chem. Lett. 2012, 3, 2303-2309.
2011
34. Rowland, M.; Bostic, H.E.; Gong, D.; Speers, A.E.; Lucas, N.; Cho, W.; Cravatt, B.F. Best, M.D.* Phosphatidylinositol (3,4,5)-trisphosphate activity probes for the labeling and proteomic characterization of protein binding partners. Biochemistry. 2011, 50, 11143−11161.
33. Best, M.D.*; Rowland, M.M.; Bostic, H.E. Exploiting bioorthogonal chemistry to elucidate protein-lipid binding interactions and other biological roles of phospholipids. Chem. Res. 2011, 44(9), 686–698.
32. Kooijman, E.E.*; Kuzenko, S.R.; Gong, D.; Best, M.D.; Folkesson, H.G. Phosphatidylinositol-4,5-bisphosphate stimulates alveolar epithelial fluid clearance in male and female adult rats. J. Physiol.-Lung Cell. Mol. Physiol. 2011, 301, L804–L811.
31. He, J.; Gajewiak, J.; Scott, J.L.; Gong, D.; Ali, M.; Best, M.D.; Prestwich, G.D.; Stahelin R.V.; Kutateladze, T.G.* Metabolically stabilized derivatives of phosphatidylinositol 4-phosphate: Synthesis and applications. Biol. 2011, 18, 1312-1319.
30. Best, M.D.* Recent developments in the generation and application of lipid probes. ASBMB Today 2011, August edition, 28-29.
29. Smith, M.D.; Best, M.D.* Characterization of protein–membrane binding interactions via a microplate assay employing liposome immobilization. Bioconjugation Protocols, 2nd edition, Editor: Sonny S. Mark. 2011, 477-489.
28. Do-Thanh, C.-L.; Rowland, M.M.; Best, M.D.* Fluorescent bis-cyclen tweezer receptors for inositol (1,4,5)-trisphosphate. Tetrahedron 2011, 67, 3803-3808.
27. Bolen, A.L.; Naren , A.P.; Yarlagadda, S.; Beranova-Giorgianni, S.; Chen, L. Norman, D.; Baker, D.L.; Rowland, M.M.; Best, M.D.; Sano T., Tsukahara, T.; Liliom, K.; Igarashi, Y.; Tigyi, G.* The phospholipase A 1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation. J. Lipid Res. 2011, 52, 958-970.
2010
26. Best, M.D.*; Zhang, H.; Prestwich, G.D. Inositol polyphosphates, diphosphoinositol polyphosphates and phosphatidylinositol polyphosphate lipids: structure, synthesis, and development of probes for studying biological activity Prod. Rep. 2010, 27, 1403-1430.
25. Rowland, M.M.; Best, M.D.* Reeling in the Catch: Advancing Cleavable Linkers for Proteomics. Chem. Biol. 2010, 17, 1166-168. (Invited preview article).
24. Zhan, *; Jiang, K.; Smith, M.D.; Bostic, H.E.; Best, M.D.*; Auad, M.L. Ruppel, J.V., Kim, C.; Zhang, X.P. Photocurrent generation from porphyrin/fullerene complexes assembled in a tethered lipid bilayer. Langmuir 2010, 26(19), 15671–15679.
23. Hoeglund, A.B.; Bostic, H.E.; Howard, A.L.; Wanjala, I.W.; Best, M.D.; Baker, D.L.*; Parrill, A.L.* Optimization of a pipemidic acid-based autotaxin inhibitor. J. Med. Chem. 2010, 53, 1056–1066.
2009
22. Best, M.D.* Click chemistry and bioorthogonal reactions: Unprecedented selectivity in the labeling of biological molecules. Biochemistry 2009, 48, 6571-6584.
21. Smith, M.D.; Sudhahar, C.G.; Gong, D.; Stahelin, R.V.; Best, M.D.* Modular synthesis of biologically active phosphatidic acid probes using click chemistry. Mol. Biosyst. 2009, 5, 962-972.
20. Gong, D.; Smith, M.D.; Manna,D.; Bostic, H.E., Cho, W.; Best, M.D.* Microplate-based characterization of protein-phosphoinositide binding interactions using a synthetic biotinylated headgroup analogue. Bioconjugate Chem. 2009, 20, 310-316.
19. Losey, E.A.; Smith, M.D.; Meng, M.; Best, M.D.* Microplate-based analysis of protein–membrane binding interactions via immobilization of whole liposomes containing a biotinylated anchor. Bioconjugate Chem. 2009, 20, 376-383.
18. Rowland, M.M.; Best, M.D.* Modular synthesis of bis(monoacylglycero)phosphate for convenient access to analogues bearing hydrocarbon and perdeuterated acyl chains of varying length. Tetrahedron 2009, 65, 6844–6849.
17. Gong, D.; Bostic, H.E.; Smith, M.D.; Best, M.D.* Synthesis of modular headgroup conjugates corresponding to all seven phosphatidylinositol polyphosphate isomers for convenient probe generation. Eur. J. Org. Chem. 2009, 48, 4170–4179.
2008
16. Smith, M.D.; Gong, D.; Sudhahar, C.; Reno, J.C.; Stahelin, R.V.; Best, M.D.* Synthesis and convenient functionalization of azide-labeled diacylglycerol analogues for modular access to biologically active lipid probes.Bioconjugate Chem. 2008, 19, 1855-1863. Publications resulting from previous positions
Publications prior to Tennessee
2006
15. Huang, C.-Y.; Thayer, D.A.; Chang, A.Y.; Best, M.D.; Hoffman, J.A., Head, S.; Wong, C.-H.* Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen. Proc. Natl. Acad. Sci. U.S.A. 2006, 103(1), 15-20.
2005
14. Calarese, D.A.; Lee, H.-K; Huang, C.-Y.;Best, M.D.; Astronomo, R.; Stanfield, R.L.; Katinger, H.; Burton, D.; Wong, C.-H.*; Wilson, I.A.* Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proc. Natl. Acad. Sci. U.S.A. 2005, 102(38), 13372-13377.
13. Brik, A.; Wu, C.-Y.; Best, M.D.; Wong, C.-H.* Tetrabutylammonium fluoride-assisted rapid N9-alkylation on purine ring: application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ. Bioorg. Med. Chem. 2005, 13, 4622-4626.
2004
12. Bryan, M.C.; Fazio, F.; Lee, H.-K.; Huang, C.-Y.;Chang, A.; Best, M.D.; Calarese, D.A.; Blixt,O.; Paulson, J.C.; Burton, D.; Wilson, I.A.; Wong, C.-H.* Covalent display of oligosaccharide arrays in microtiter plate. J. Am. Chem. Soc. 2004, 126, 8640-8641.
11. Best, M.D.; Brik, A.; Chapman, E.; Lee, L.V.; Cheng W.-C., Wong, C.-H.* Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening. ChemBioChem 2004, 5(6), 811-819.
10. Hanson, S.R.; Best, M.D.; Bryan, M.C.; Wong, C.-H.* Chemoenzymatic synthesis of oligosaccharides and glycoproteins. Trends Biochem. Sci 2004, 29(12), 656-663.
9. Hanson, S.R.; Best, M.D.; Wong, C.-H.* Sulfatases: Structure, mechanism, biological activity, inhibition and synthetic utility. Angew. Chem. Int. Ed. 2004, 43(43), 5736-5763.
8. †Chapman, E.; †Best, M.D.; Hanson, S.R.; Wong, C.-H.* Sulfotransferases: Structure, mechanism, biological activity, inhibition and synthetic utility. Angew. Chem. Int. Ed. 2004, 43(27), 3526-3548. † Co-first authors
7. Zhong, Z.; Snowden, T.S.; Best, M.D.; Anslyn, E.V.* Rate of enolate formation is not very sensitive to the hydrogen bonding ability of donors to carboxyl oxygen lone pair acceptors; a ramification of the principle of non-perfect synchronization for general-base-catalyzed enolate formation. J. Am. Chem. Soc. 2004, 126(11), 3488-3495.
2003
6. Best, M.D.; Anslyn, E.V.* A fluorescent sensor for 2,3-bisphosphoglycerate using a europium tetra-N-oxide bis-bipyridine complex for both binding and signaling purposes. Chem. Eur. J. 2003, 9(1), 51-57.
5. Best, M.D.; Tobey, S.L.; Anslyn, E.V.* Abiotic guanidinium containing receptors for anionic species. Coord. Chem. Rev. 2003, 240(1-2), 3-15.
4. Worm, K.; Matsumoto, K.; Best, M.D.; Anslyn, E.V.* Preorganized bis-zinc phosphodiester cleavage catalysts possessing natural ligands: a lesson pertinent to bimetallic artificial enzymes. Chem. Eur. J. 2003, 9(3), 741-747.
2001
3. Cabell, L.A.; Best, M.D.; Lavigne, J.L.; Schneider, S.E.; Perreault, D.M.; Monahan, M.-K.; Anslyn, E.V.* Metal triggered fluorescence sensing of citrate using a synthetic receptor. J. Chem. Soc., Perkin Trans. 2 2001, 3, 315-323.
1998
2. Weitz, A.; Shabtai, E.; Rabinovitz, M.*; Bratcher, M.S.; McComas, C.C.; Best, M.D.; Scott, L.T.* Dianions and tetraanions of bowl-shaped fullerene fragments dibenzo[a,g]corannulene and dibenzo[a,g]cyclopenta[kl]corannulene. Chem. Eur. J. 1998, 4(2), 234-239.
1997
1. Chen, G.; Ma, S.; Cooks, R.G.*; Bronstein, H.E.; Best, M.D.; Scott, L.T.* Electron affinities and C60 anion clusters of certain bowl-shaped polycyclic aromatic hydrocarbons. J. Mass. Spectrom. 1997, 32(12), 1305-1309.